Clinical Study and Comparison of Magnesium and Antioxidants Between Mothers and Neonate by ICP-OES and Elisa Technique in Basrah Southern of Iraq

Abstract

The extent and clarity of the putative maternal and neonatal antioxidant effects related to magnesium intake during pregnancy are currently restricted. Objectives: The primary objective of this research is to investigate the potential correlations between levels of magnesium exposure in maternal and cord serum. Additionally, the study sought to explore any potential links between maternal magnesium exposure levels and neonatal outcomes. The research was carried out in the urban area of Basrah, spanning from March 2022 to July 2022, including two distinct cohorts.: the first was the mother and the second was the neonate.  The study included measuring the mother's magnesium concentration, total antioxidant capacity (TAO), and the oxidant malonaldehyde (MDA), and comparing it to the umbilical cord blood, which represents the blood of the newborn.  The results indicated that the concentration of (TAO) in the mother is higher than that in the neonate, while the concentration of magnesium in the neonate is higher than its concentration in the mother. Magnesium status is relevant to neonate growth during pregnancy and newborn growth during the perinatal period.  Furthermore, magnesium is able to influence neonate programming and disease presentation in childhood or adulthood. In order to study its role in neonate health, this review focuses on the balance of this mineral, analyse its normal values, the causes of hypomagnesemia that causes increased (MDA), and the diseases associated with changes in the value of magnesium during pregnancy.  The data presented here clearly indicate an association between magnesium status and disease that begins in utero and extends into childhood and adulthood.